• 四川大學(xué)華西醫(yī)院耳鼻咽喉—頭頸外科，四川成都 610041;

目的:探討阻塞性睡眠呼吸暫停低通氣綜合征（Obstructive Sleep ApneaHypopnea Syndrome，OSAHS）的危險(xiǎn)因素。方法:192例就診于睡眠實(shí)驗(yàn)室的患者進(jìn)行標(biāo)準(zhǔn)化問卷填調(diào)查，測量頸圍、腰圍、臀圍、身高和體重及整夜多導(dǎo)睡眠監(jiān)測，分析性別、年齡和肥胖因素與OSAHS嚴(yán)重程度的關(guān)系。結(jié)果:OSAHS患者在癥狀、病情及人體測量學(xué)指標(biāo)方面存在性別差異；發(fā)病年齡主要分布在31~60歲；OSAHS患者的體重指數(shù)（Body Mass Index，BMI）、頸圍、腰臀比與AHI、氧減指數(shù)、最低血氧飽和度相關(guān)。結(jié)論:OSAHS的發(fā)生及嚴(yán)重程度與性別、年齡和肥胖等危險(xiǎn)因素密切相關(guān)。

引用本文： 王立曼,周光耀,李春華,雷飛,薛倩. 阻塞性睡眠呼吸暫停低通氣綜合征危險(xiǎn)因素探討?yīng)? 華西醫(yī)學(xué), 2009, 24(1): 46-49. doi: 復(fù)制

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5. Popovic RM，White DP.Upper airway muscle activity in normal women:influence of hormonal status[J].J Appl Physiol，1998，84（3）:1055-1062..
6. Wetter DW，Young TB，Bidwell TR，et al.Smoking as a risk factor for sleep disordered breathing[J].Arch Intern Med，1994，154（19）:2219-2224..
7. AncoliIsrael S，Kripke DF，Mason W，et al.Sleep apnea and periodic movements in an aging sample[J].J Gerontol，1985，40（4）:419-425..
8. AncoliIsrael S，Kripke DF，Klauber MR，et al.Sleepdisordered breathing in communitydwelling elderly[J].Sleep，1991，14（6）:486-495..
9. Bixler EO，Vgontzas AN，Ten Have T，et al.Effects of age on sleep apnea in men:Ⅰ.Prevalence and severity[J].Am J Respir Crit Care Med，1998，157（1）:144-148..
10. Sforza E，Bacon W，Weiss T，et al.Upper airway collapsibility and cephalometric variables in patients with obstructive sleep apnea[J].Am J Respir Crit Care Med，2000，161（2 Pt 1）:347-352..
11. Vgontzas AN，Papanicolaou DA，Bixler EO，et al.Sleep apnea and daytime sleepiness and fatigue:relation to visceral obesity，insulin resistance，and hypercytokinemia[J].Am J Respir Crit Care Med，2000，85（3）:1151-1158..
  1. 1. Duran J，Esnaola S，Rubio R，et al.Obstructive sleep apneahypopnea and related clinical features in a populationbased sample of subjects aged 30 to 70 yr[J].Am J Respir Crit Care Med，2001，163（3 Pt 1）:685-689..
  2. 2. 中華醫(yī)學(xué)會耳鼻咽喉科學(xué)分會.阻塞性睡眠呼吸暫停低通氣綜合征診斷依據(jù)和療效評定標(biāo)準(zhǔn)暨懸雍垂腭咽成形術(shù)適應(yīng)證（杭州）[J].中華耳鼻咽喉科雜志，2002，37:403-404..
  3. 3. Redline S，Kump K，Tishler PV，et al.Gender differences in sleep disordered breathing in a communitybased sample[J].Am J Respir Crit Care Med，1994，149（3 Pt 1）:722-726。.
  4. 4. Popovic RM，White DP.Influence of gender on waking genioglossal electromyogram and upper airway resistance[J].Am J Respir Crit Care Med，1995，152（2）:725-731..
  5. 5. Popovic RM，White DP.Upper airway muscle activity in normal women:influence of hormonal status[J].J Appl Physiol，1998，84（3）:1055-1062..
  6. 6. Wetter DW，Young TB，Bidwell TR，et al.Smoking as a risk factor for sleep disordered breathing[J].Arch Intern Med，1994，154（19）:2219-2224..
  7. 7. AncoliIsrael S，Kripke DF，Mason W，et al.Sleep apnea and periodic movements in an aging sample[J].J Gerontol，1985，40（4）:419-425..
  8. 8. AncoliIsrael S，Kripke DF，Klauber MR，et al.Sleepdisordered breathing in communitydwelling elderly[J].Sleep，1991，14（6）:486-495..
  9. 9. Bixler EO，Vgontzas AN，Ten Have T，et al.Effects of age on sleep apnea in men:Ⅰ.Prevalence and severity[J].Am J Respir Crit Care Med，1998，157（1）:144-148..
  10. 10. Sforza E，Bacon W，Weiss T，et al.Upper airway collapsibility and cephalometric variables in patients with obstructive sleep apnea[J].Am J Respir Crit Care Med，2000，161（2 Pt 1）:347-352..
  11. 11. Vgontzas AN，Papanicolaou DA，Bixler EO，et al.Sleep apnea and daytime sleepiness and fatigue:relation to visceral obesity，insulin resistance，and hypercytokinemia[J].Am J Respir Crit Care Med，2000，85（3）:1151-1158..