將100只日本大耳白隨機(jī)分為正常對(duì)照組（10只），實(shí)驗(yàn)組又分為膽道單純不全梗阻組（45只）和膽道不全梗阻加感染組（45只）。實(shí)驗(yàn)組術(shù)后3、7、14和21天分別動(dòng)態(tài)檢測(cè)膽囊免疫球蛋白（Ig）分泌細(xì)胞的含量，并比較其變化。結(jié)果顯示：正常兔膽囊粘膜雖存在Ig分泌細(xì)胞，但數(shù)量較少。單純梗阻組3、7和14天膽囊粘膜IgG和IgA分泌細(xì)胞無明顯變化，梗阻加感染組各時(shí)相Ig分泌細(xì)胞明顯高于對(duì)照組（P lt;0.001），以IgG分泌細(xì)胞最為明顯。細(xì)菌抗原的刺激是膽囊Ig分泌細(xì)胞特異性增殖的主要因素，膽囊是膽道系統(tǒng)Ig產(chǎn)生的重要場所，膽囊Ig分泌細(xì)胞與結(jié)石的形成有密切關(guān)系。
引用本文： 曾勇 ,肖路加,張尚福. 兔膽紅素鈣結(jié)石成石過程中膽囊免疫球蛋白分泌細(xì)胞含量的變化. 中國普外基礎(chǔ)與臨床雜志, 1997, 4(2): 75-77. doi: 復(fù)制
版權(quán)信息： ?四川大學(xué)華西醫(yī)院華西期刊社《中國普外基礎(chǔ)與臨床雜志》版權(quán)所有，未經(jīng)授權(quán)不得轉(zhuǎn)載、改編
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