目的 觀察冷基循環(huán)微波聚能刀(PMCT)聯(lián)合化療治療晚期非小細(xì)胞肺癌(NSCLC)的療效和對(duì)患者生活質(zhì)量的影響。方法 80例NSCLC患者隨機(jī)分為PMCT聯(lián)合化療組和單純化療組,每組40例,兩組化療方案均為順鉑+艾素。比較兩組半年期的臨床療效、生存率和生活質(zhì)量評(píng)分。結(jié)果 PMCT聯(lián)合化療組和單純化療組患者治療3個(gè)月后的有效率分別為52.5%(21/40)和32.5%(13/40),有顯著差異(P lt;0.05)。PMCT聯(lián)合化療組治療半年生存率為87.5%(35/40),單純化療組患者半年生存率為62.5%(25/40),差異有統(tǒng)計(jì)學(xué)意義(P lt;0.05)。PMCT聯(lián)合化療組治療6個(gè)月后生活質(zhì)量總評(píng)分為(143.6±2.4)分,KPS評(píng)分為(93±4)分;單純化療組治療6個(gè)月后生活質(zhì)量總評(píng)分為(121.5±3.5)分,KPS評(píng)分為(79±3)分,差異有統(tǒng)計(jì)學(xué)意義(P均 lt;0.05)。結(jié)論 PMCT聯(lián)合化療治療晚期NSCLC療效優(yōu)于常規(guī)化療。
引用本文: 遆新宇,李圣青,劉阿茹,歐陽海峰,趙峰,吳昌歸. 冷基循環(huán)微波聚能刀聯(lián)合化療與單純化療治療晚期非小細(xì)胞肺癌的近期療效比較. 中國呼吸與危重監(jiān)護(hù)雜志, 2008, 08(3): 174-176. doi: 復(fù)制
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