目的 探討纖維支氣管鏡( 纖支鏡) 及支氣管肺泡灌洗( BAL) 在免疫損害宿主肺部病變中的診斷價(jià)值及并發(fā)癥。方法 收集31 例免疫損害宿主因肺部病變行纖支鏡檢查的臨床資料以及BALF 病原學(xué)檢查結(jié)果。除常規(guī)的微生物檢查外, 采用分子檢測(cè)方法檢測(cè)巨細(xì)胞病毒以及呼吸道病毒。結(jié)果 所有病例均進(jìn)行了BAL, 纖支鏡總的診斷率為65% , 且在感染性疾病中的診斷率較非感染性疾病為高, 分別為86% 和25% 。通過分子檢測(cè)發(fā)現(xiàn)4 例巨細(xì)胞病毒和3 例呼吸道病毒感染病例。結(jié)論 纖支鏡及BAL 對(duì)于明確免疫損害宿主肺部病變的病因是有效和安全的。分子檢測(cè)可幫助提高診斷率。
引用本文： 張鵬宇,張國(guó)清,謝國(guó)剛,金先橋,周新. 支氣管鏡及支氣管肺泡灌洗在免疫損害宿主肺部病變?cè)\斷中的應(yīng)用. 中國(guó)呼吸與危重監(jiān)護(hù)雜志, 2009, 09(3): 259-261. doi: 復(fù)制
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