• 四川大學(xué)華西醫(yī)院血液科（成都，610041）;

【摘要】 目的  總結(jié)應(yīng)用Hyper-CVAD/MA強(qiáng)力化療方案治療成人急性淋巴細(xì)胞白血病的護(hù)理措施，以提高護(hù)士對(duì)相關(guān)患者的護(hù)理水平。 方法  2004年6月-2009年2月，應(yīng)用Hyper-CVAD/MA強(qiáng)力化療方案治療80例急性淋巴細(xì)胞白血病患者，在化療過(guò)程中，護(hù)士密切監(jiān)護(hù)并觀察化療藥物的不良反應(yīng)，積極給予護(hù)理措施。 結(jié)果  80例急性淋巴細(xì)胞白血病患者均順利完成化療并出院，未發(fā)生與護(hù)理相關(guān)的不良反應(yīng)。 結(jié)論  應(yīng)用Hyper-CVAD/MA強(qiáng)力方案治療成人急性淋巴細(xì)胞白血病，護(hù)理工作十分重要。嚴(yán)密觀察病情，強(qiáng)化化療護(hù)理，可以有效地預(yù)防和減輕毒副反應(yīng)的發(fā)生。
【Abstract】 Objective  To summarize the nursing measures of patients with adult acute lymphocytic leukemia treated with hyper-CVAD/MA chemotherapy regimen, a dose-intensive regimen, and improve the level of nursing care. Methods  Eighty patients with acute lymphocytic leukemia treated by hyper-CVAD/MA regimen in this hospital were included June 2004 to February 2009.The patients were closely monitored and given nursing interventions.The drug adverse reactions were observed. Results  All patients completed scheduled regimen and discharged successfully without any adverse events associated with nursing care. Conclusion  The nursing interventions are very important for the patients with adult acute lymphocytic leukemia treated with hyper-CVAD/MA regimen, and close observation on the patients and strengthening nursing care can effectively prevent and mitigate the occurrence of toxicity.

引用本文： 曾慶會(huì),張川莉,萬(wàn)永鳳. Hyper-CVAD/MA強(qiáng)力化療方案治療成人急性淋巴細(xì)胞白血病的護(hù)理. 華西醫(yī)學(xué), 2010, 25(7): 1357-1359. doi: 復(fù)制

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  2. 2. Kantarjian HM, O’Brien S, Smith TL, et al. Result of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia[J]. J Clin Oncol, 2000, 18(3): 547-561.
  3. 3. Kantarjian HM, Thomas D, O’Brien, et al. Long-term follow-up results of hyperfractionated cyclophosphamide, vincristine, doxorubincin, and dexamethasone(Hyper-CVAD), A does-intensive regimen, in adult acute lymphocytic leukemia[J]. Cancer, 2004, 101(12): 2788-2801.
  4. 4. 魏明霞, 申徐良, 秦小琪, 等. Hyper-CVAD/MA治療急性淋巴細(xì)胞白細(xì)胞臨床觀察[J]. 長(zhǎng)治醫(yī)學(xué)院學(xué)報(bào), 2008, 22(6): 415-417.
  5. 5. 張世君, 李蘭花. 大劑量阿糖胞苷治療難治性白血病病人的護(hù)理[J]. 護(hù)理學(xué)雜志, 2002, 17(9): 655-656.